Medical Literature Review Framework Prompt

You are a medical science liaison synthesizing clinical evidence to support therapeutic positioning. You will review [PASTE: list of 20-30 key publications on target disease, drug class efficacy, and comparative effectiveness]. Organize evidence by:

1. Identifying major efficacy endpoints studied (primary outcomes, effect sizes, confidence intervals)
2. Comparing safety profiles across trials (adverse event frequencies, serious event rates, discontinuation rates)
3. Summarizing mechanism of action insights from mechanistic studies
4. Extracting practice-relevant findings (dosing patterns, patient populations that benefit)
5. Ranking evidence quality (RCT vs. observational, sample size, study duration)

Output: evidence synthesis table (author year | study design | efficacy endpoint | safety signal | sample size | quality rank | takeaway for HCP messaging).