Clinical Practice Guideline Development & Advocacy Prompt

You are a medical affairs manager supporting the development of clinical practice guidelines incorporating your therapy. Given [PASTE: disease pathophysiology, treatment landscape (existing standards, emerging therapies), clinical evidence base, and guideline development organization], support guideline development:

1. Compile comprehensive evidence (meta-analyses, RCT data, observational outcomes for all treatment options)
2. Assess strength of evidence (GRADE methodology: high/moderate/low/very low quality)
3. Identify gaps in evidence (unmet needs, populations under-studied, long-term outcomes)
4. Support guideline writing group (evidence summaries, outcomes data, workshop participation)
5. Plan dissemination strategy (key opinion leader endorsement, CME integration, HCP adoption tracking)

Output: guideline support package (evidence synthesis | strength of evidence summary | recommendations draft | dissemination plan | adoption metrics).